Advanced Physical and Computational Techniques to Investigate Protein Dynamics
26.-28. April 2021
News from Feb 15, 2021
Day 1 (April 26, 2021)
09:00 – 09:30: Registration (30 min)
09:30 – 10:00: Welcome (30 min) Dr. Stefan Jorda, Christian Freund, Frank Noé
Session I 10:00 – 18:15 NMR methods for probing dynamics
10:00 – 10:45 Christian Freund, Freie Universität Berlin, Germany (45 min)
Dynamic aspects of antigen presentation by MHC class II molecules
10:45 – 11:30 Michael Sattler, Helmholtz Zentrum München, Germany (45 min)
Combining NMR and integrative structural biology to study dynamics and allostery in protein complexes
11:30 – 12:15 Birthe B. Kragelund, University of Copenhagen, Denmark (45 min)
Dynamic protein complexes in biology - how can NMR help?
12:15 – 13:00 Lunch break (45 min)
13:00- 14:00 Cultural event (1 hr)
14:00 – 16:00 Poster session I – 20 posters (2 hr)
16:00 – 16:45 Nikolaos Sgourakis, University of Pennsylvania, Pennsylvania, USA (45 min)
Anatomy of a peptide trap: dynamics of MHC-I/chaperone complexes
16:45 – 17:30 Lewis E. Kay, University of Toronto, Toronto, Canada (45 min)
TBD
17:30 – 18:15 Julie D. Forman-Kay, University of Toronto, Toronto, Canada (45 min)
TBD
18:15 – 19:00 Roundtable discussion I: Perspectives of NMR (45 min)
Day 2 (April 27, 2021)
Session II 09:00 – 18:15 Molecular dynamics simulation and Free energy landscapes
09:00 – 09:45 Frank Noé, Freie Universität Berlin, Germany (45 hr)
TBD
09:45 – 10:30 Kresten Lindorff-Larsen, University of Copenhagen, Denmark (45 hr)
TBD
10:30 – 11:15 Gianni De Fabritiis, Universitat Pompeu Fabra, Spain (45 min)
TBD
11:15 – 12:00 Cecilia Clementi, Freie Universität Berlin, Germany (45 min)
Learning protein models from simulation andexperimental data
12 :00 – 13:00 Lunch break (1 hr)
13:00 – 14:00 Cultural event (1 hr)
14:00 - 16:00 Poster session II – 20 posters (2 hr)
16:00 – 16:45 Carlo Camilloni, University of Milano, Italy (45 min)
Modelling biomolecules structure and dynamics by combining small-angle x-ray scattering and computer simulations
16:45 – 17:30 Bert de Groot, Max Planck Institute, Germany (45 min)
17:30 – 18:15 Rommie Amaro, University of California, San Diego, USA (45 min)
Application of advanced simulation and analysis methods to real systems
18:15 – 19:00 Roundtable discussion II: Future aspects of theoretical approaches (45 min)
Day 3 (April 28, 2021)
Session III 09:00 – 10:30 Structure and dynamics of Macromolecular Systems
09:00 – 09:45 Oliver Daumke, Max-Delbrück-Centrum für Molekulare Medizin (45 min)
The mechanism of dynamin in membrane constriction – From static snapshots to dynamic models
09:45 – 10:30 Christian Spahn, Charité Universitätsmedizin Berlin (45 min)
TBD
10:30 – 11:00 Coffee Break (30 min)
11:00 – 11:45 Ben Schuler, University of Zurich, Switzerland (45 min)
Dynamics and Interaction Mechanisms of Intrinsically Disordered Proteins from Single-Molecule Spectroscopy
11:45 – 12:30 Enrica Bordignon, Bochum University, Germany (45 min)
TBD
12:30 – 13:30 Lunch break (1 hr)
13:30 – 14:15 Markus Wahl, Freie Universität Berlin, Germany (45 min)
RNA polymerase dynamics during transcription termination and anti-termination
14:15 – 15:00 Alke Meents, DESY/Universität Hamburg, Germany (45 min)
TBD
15:00 – 15:45 Best poster presentations – 3 posters (45 min)
15:45 – 16:15 Coffee break (30 min)
16:15 – 17:00 Brian Baker, University of Notre Dame, USA (45 min)
TBD
17:00 – 17:45 Stefan Raunser, Max-Planck-Institute Dortmund, Germany (45 min)
TBD
17:45 – 18:30 Roundtable discussion III – Towards cellular structural biology (45 min)
18:30 Final Remarks