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Synthetically and industrially important reactions, concept of retrosynthesis (synthons, retrons, synthesis equivalents, conversion of functional groups), modern radical reactions, electrophilic aromatic second substitution (substituent effects), eliminations (E1/E2/E1cb) and their stereochemical implications, Ylide, Wittig reaction and its variants (stereochemical control), nucleophilic addition to C=O double bonds, Dunitz-Bürgi-Lehn trajectories, reactions with polarity reversal of reactivity, synthesis of 1,n-difunctionalized compounds, pericyclic reactions, sextet rearrangements, catalysis using the example of palladium-catalyzed cross-couplings.