Research Interests
Oral drug delivery systems (DDS)
- multiparticuate DDS
- pelletization ({extrusion/spheronization}, rotorgranulation)
- minitablets
- coating
- compression of pellets into tablets
- pulsatile DDS (tablets, capsules, pellets)
- gastroretentive DDS
- matrix tablets (water-soluble and - insoluble carriers)
- fast dissolving dosage forms (tablets, sponges, films, capsules)
- delivery of poorly soluble drugs
- formulation of moisture-sensitive drugs
Coating technology
- aqueous polymer dispersions
- aqueous/organic polymer solutions
- coating with natural polymers (e.g., shellac, zein)
- coating of pellets, tablets, soft and hard gelatin capsules
- polymer powder coating
Microencapsulation
- micro-/nanoparticles (solvent evaporation, spray drying, grinding, {SCF})
- incorporation micro-/nanoparticles into a final dosage form
- liquid controlled release DDS
Biodegradable DDS
- implants (melt compression, extrusion)
- microparticles
- in-situ microparticle/ implant system
- lipid DDS (cubic phase DDS, microparticles)
- delivery systems for larger molecules (proteins, peptides, oligonucleotides)
Miscellaneous projects
- mucoadhesive DDS (nasal, buccal)